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Etodolac

[ English name ] Etodolac

[ CAS name ] 1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4- b ]indole-1-acetic acid

[ Molecular formula ] C17H21NO3

[ CAS NO ] 41340-25-4

[ Molecular weight ] 287.37

[ Structure formula ]   

[ Properties ]
Crystals from hexane/chloroform , mp 145-148 °C , pKa 4.65. Insol in water. Sol in alcohols, chloroform, DMSO, aqueous polyethylene glycol.

[ Specifications ]

[ Function and use ]
Etodolec is used for the treatment of inflammation and pain caused by osteoarthritis and rheumatoid arthritis as well as soft tissue injuries, such as tendonitis and bursitis. Etodolac is alse used for rapid relief of mild to moderate pain, such as with menstrual cramps.

[ Usage and dosage ]
Etodolac Extended Release Table ( Lodine XL )
1) General Pain Relief: Take 200 to 400 milligrams every 6 to 8 hours as needed. Ordinarily you should not take more than 1,000 milligrams a day, although your doctor may ircrease the dose to 1,200 milligrams a day if absolutely necessary.
2)Osteoarthritis and Rheumatoid Arthritis:
The starting dose of Lodine is 300 milligrams 2 or 3 times a day, or 400 or 500 milligrams twice a day. The usual daily maximum rangs from 600 to 1,000 milligrams, although you doctor may prescribe as much as 1,200 milligams a day if necessary.
The usual dose of Lodine XL is 400 to 1,200 milligrams taken once a day.
Your doctor will stick with the lowest close that proves effective.
3)Children: The safety and effectiveness of Lodine have not bee established in children.

[ Conveyance and storage ]
Under dry and ventilate condition in storage and transportation. Keep away from moisture , sunshine, food, seed and forage .

[ Packing ]
25 kg plastic woven bag or cardboard drum lined with plastic bag.


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